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Rehab / Treatment of Chronic Intoxication Caused By Alcohol and Alcohol-induced Facilitation of Liver Damage. METADOXIL N10/N30

Last updated on January 4, 2023


Metadoxil 500 mg Tablet is a liver-protective agent used in the treatment of alcohol intoxication and fatty liver. This medication works by accelerating the clearance of alcohol from the blood. It is also being used nowadays for the treatment of ADHD (attention deficit hyperactivity syndrome) and Fragile X syndrome. This medicine is used to treat alcohol intoxication (alcohol poisoning), a condition associated with drinking an excess amount of alcohol within a short period of time. The symptoms of alcohol intoxication may include slurred speech, incoordination, mood and behavior changes, coma (in rare cases), confusion, memory loss, etc. This medicine is used to treat alcoholic fatty liver, a condition characterized by increased deposits of fat in the liver. The symptoms of a fatty liver may include weight loss, abdominal pain, a feeling of tiredness, etc

Uses and active ingredients

Alcohol Intoxication. Chronic Alcoholism. Alcohol Withdrawal Syndrome. Complex Therapy of Liver Diseases, Especially Alcohol Etiology.

Metadoxil 500 g Metadoxine N10 tablets Italy

Active ingredient: Pyridoxine L-2 pyrrolidone 5-carboxylate (methadoxine) – 500 mg. Excipients: Microcrystalline cellulose, magnesium stearate. Metadoxine is able to accelerate the elimination of alcohol from the blood and tissues, to help restore the functional structure of the liver and  to relieve neuro-psychological disorders associated with alcohol intoxication. Metadoxine also seems to be safe; in more than 15 years of post-marketing surveillance only minor aspecific and reversible events were monitored in patients exposed to the treatment. In this review the preclinical and clinical results obtained using metadoxine in acute and chronic alcohol intoxication are reported.

How to take Metadoxil

Metadoxil 500 g Metadoxine N30 tablets Italian
Large package Metadoxil N30

Combined therapy for chronic alcoholism: 1 tablet 2 times a day (1000 mg) 15-30 minutes before meals, the dose can be increased to 3 tablets (1500 mg) per day. The course of therapy should be at least 90 days.

Packaging contains Metadoxil comes in the form of tablets: 500 mg per tablet, 10/30 tablets per pack.

Daily servings: 2-3 tablets
Pack size (Servings per container): 10 or 30 tablets (3-15 daily doses)

Storage. Keep this medicine out of the sight and reach of children. This medicine requires no special storage conditions. Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment.

Side-effects, precautions and interactions

Major & minor side effects for Metadoxil 500 Tablet
Itching of skin
Shaking of the hands or feet
Abdominal pain
Fast heartbeat

Is It safe with alcohol?
Metadoxil may cause symptoms such as flushing, increased heartbeat, nausea, thirst, chest pain and low blood pressure with alcohol.

The picture is for illustration only. The packaging can be changed by the manufacturer. All packs include English informational leaflet.


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