Last updated on September 29, 2023
The active ingredient of Mildronate-Grindeks is meldonium dihydrate (meldonium).
Uses and active ingredients
Meldonium is a structural analogue of a substance contained in every cell of the body – gamma-butyrobetaine. The action of this drug is based on a positive effect on the energy metabolism of the body, as well as on the easy activation of the central nervous system. During physical exercise, Mildronate-Grindeks restores the balance of the processes of supply and consumption of oxygen in cells, activates those metabolic processes that require less oxygen consumption for energy production.
Usually, under conditions of increased stress, the body quickly runs out of strength, but as a result of the use of Mildronate-Grindeks, the body gets used to withstanding the load, uses oxygen sparingly and quickly restores energy reserves to prepare for new loads.
Possessing the functions of gamma-butyrobetaine, Mildronate-Grindeks is able to accelerate the transmission of nerve impulses in the body, thus, all reactions become faster, and the overall metabolism of the body improves. Therefore, when using Mildronate-Grindeks, a tonic effect is felt – memory improves, thinking accelerates, mobility increases, and the body’s resistance to unfavorable conditions increases.
Mildronate-Grindeks is used in combination therapy in the following cases: – decrease in working capacity, physical and psycho-emotional overload; – recovery period after cerebrovascular accident, traumatic brain injury and encephalitis.
Composition. Each hard capsule contains 250 mg of meldonium dihydrate. Remaining Ingredients: Potato Starch, Silica, Calcium Stearate. Hard gelatin capsule (body and cap): titanium dioxide, gelatin.
Method of Administration
Adults:
The dose is 500-1000 mg (2-4 capsules) per day. The daily dose can be taken immediately or divided into two doses. The maximum daily dose is 1000 mg. Duration of treatment is 4-6 weeks. The course of treatment can be repeated 2-3 times a year in consultation with the doctor.
Elderly patients:
Elderly patients with impaired liver and / or kidney function may need to reduce the dose of Mildronate-Grindeks.
Patients with renal impairment:
Patients with mild to moderate kidney problems should take lower doses of Mildronate-Grindeks.
Patients with impaired liver function:
Patients with mild to moderate liver problems should take lower doses of Mildronate-Grindeks.
Use in children and adolescents:
There is no data on the safety and effectiveness of Mildronate-Grindeks in children and adolescents (under 18 years of age), therefore this medicine should not be used in children and adolescents.
Storage. Do not store at a temperature higher than 25°C/77°F. Keep out of the sight and reach of children. Do not use after the expiry date which is stated on the package. The expiry date refers to the last day of that month.
Warnings
Mildronate should not be used if you are allergic to meldonium dihydrate or any of the excipients of this medicine. Mildronate may potentiate the effects of some cardiovascular drugs such as glycerol trinitrate, nifedipine, beta-blockers, antihypertensives, and peripheral vasodilators.
The picture is for illustration only. The packaging can be changed by the manufacturer. All packs include English informational leaflet.
